VAZALORE® is heart protection with the stomach in mindTM
A UNIQUE
DELIVERY SYSTEM
FOR THIS
LIFE-SAVING DRUG
VAZALORE IS SPECIALLY DESIGNED TO HELP REDUCE LOCAL GASTRIC
INJURY WHILE MAINTAINING FULL ASPIRIN BIOAVAILABILITY
VAZALORE is a liquid-filled capsule containing aspirin preassociated with a unique phospholipid to prevent the aspirin from interacting with similar naturally occurring phospholipids in the gastric mucosal barrier, helping to avoid local gastric injury.
THE COMPLEX
VAZALORE contains a proprietary pH-dependent complex of phospholipid excipients and aspirin. Once the capsule dissolves in the stomach, the complex is released, remaining stable in low-pH environments.
THE PROTECTION
While in low-pH environments the aspirin remains sequestered in the phospholipid complex to limit its direct contact with the stomach.
THE ABSORPTION
As pH rises within the GI tract (e.g., across the gastroduodenal mucosal barrier and within the mucosal cells) the aspirin disassociates from the complex and is freed to be quickly and completely absorbed, delivering predictable antiplatelet effects.1
- Angiolillo DJ, Bhatt DL, Lanza F, et al. Pharmacokinetic pharmacodynamic assessment of a novel, pharmaceutical lipid–aspirin complex: results of a randomized, crossover, bioequivalence study. J Thromb Thrombolysis. 2019;48(4):554-562.